The Academic Medical Center Patient Safety Organization (AMC PSO) convened Emergency Medicine Leaders to share their expertise and opinions regarding patient safety issues relevant to the Emergency Department (ED) setting. Participants discussed case studies, as well as emerging technologies and new strategies that are now available to complement existing patient safety protocols aimed at reducing ED adverse events. The AMC PSO sponsored this meeting to propagate CRICO’s established mission of helping healthcare providers turn credible patient safety data into effective action.