A 55-year-old obese woman with a history of hypertension presented to her primary care physician (PCP) with complaints of weight loss and diarrhea with mild, occasional cramps. She also complained of joint pain and was diagnosed with osteoarthritis. The PCP characterized the diarrhea as “functional;” a hemocult test in the office, however, was guaiac-positive. Her note stated that the guaiac-positive stools “raise concerns for some form of colitis, polyps, or possible malignancy.” The patient’s rectal and abdominal examination was otherwise normal. The addendum to her office note indicated that one additional stool sample tested as guaiac-positive and that “it is likely that she will need a colonoscopy.” The patient was also diagnosed with hypertension and an elevated cholesterol. In a follow-up visit with the nurse for a blood pressure check the following month, the patient indicated she was anxious regarding the blood in her stool.
The patient visited the PCP several times over the next several months, primarily for follow-up related to the hypertension, which was monitored very closely by the PCP. At no time during any of these visits was the diarrhea, the blood in the stool, or the colonoscopy discussed with the patient. When the patient was seen for a physical examination four months later, the PCP omitted the rectal examination altogether. Eight months after that, the patient presented with a complaint of right lower quadrant discomfort which had persisted for more than 10 days. On exam, the physician noted a sense of fullness in the right lower quadrant with tenderness to touch, although no mass was palpated and the stool was guaiac negative. The PCP ordered an abdominal CT scan, colonoscopy, and blood work.
The CT scan documented cecal thickening and the colonoscopy demonstrated a large ulcerated lesion in the cecum. Biopsies were positive for adenocarcinoma. The patient underwent a colectomy and the findings at the time of surgery included peritoneal metastasis. The patient subsequently underwent a year-long course of palliative chemotherapy. She died two years later.